There is going to an emphasis on the weekly game plan as the Eagles look to create and then take advantage of personnel matchups. Receivers will go in motion to help with an easy release off of the line of scrimmage. Personnel groupings will change from play to play. Backs will move out of the formation and line up in a variety of spots.
In other words, it's going to look a lot like the offense looked in the Andy Reid era when the Eagles kept their turnovers down and generally ranked among the league's best in drive efficiency without, for most of those seasons, top-tier individual talent up and down the lineup.